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Mecobalamin also contributes to the normal production of red blood cells and participates in DNA synthesis, making it an important nutrient for healthy cell division and tissue maintenance

doi: 10.7150/ijbs.12152 82 TongBYuanXDouYWuXChouGWangZet al

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The key signaling pathways investigated include the nuclear factor erthriod 2 related factor 2 (Nrf2) activation cascade which leads to the upregulation of phase 2 detoxification genes heme oxygenase (HO1), superoxide dismutase and catalase (CAT), inhibition of the inflammatory signaling pathway of nuclear kappa B (NF-B), modulation of PI3K/Akt/mTOR pathways in cancer cells and activation of the adenosine monophosphate activated protein kinase (AMPK) for metabolic regulation