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At low dose synthetic color, the liver revealed a disruption of hepatic cells near the central vein, and hepatocellular damaged

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RP-HPLC Used to determine: Chemical purity Degradation products Relative stability over time LC-MS Used to identify: Molecular weight changes Oxidation Deamidation Fragmentation UV-Visible Spectrophotometry Useful for detecting: Oxidation Color changes Chromophore alterations Dynamic Light Scattering (DLS) Used to measure: Aggregation Particle size Solution homogeneity Myth vs