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While not everyone with IgG4-RD experiences headaches, the disease can impact areas that lead to persistent or severe headaches, such as: The meninges: These protective brain layers can thicken and become inflamed (hypertrophic pachymeningitis), resulting in ongoing, sometimes debilitating headaches

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Gut dysbiosis can trigger a series of immune responses, weakening intestinal barrier function and allowing both endogenous and exogenous antigens to enter the bloodstream more easily and activate systemic immune responses

These claims are primarily based on centuries of Ayurvedic use and anecdotal evidence