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doi: 10.3389/fphys.2026.1783596 Received 11 January 2026 Revised 11 February 2026 Accepted 20 February 2026 Published 12 March 2026 Corrected 24 April 2026 Volume 17 - 2026 Edited by Anand Thirupathi, Ningbo University, China Reviewed by Logan Moore, Texas Wesleyan University, United States Yuxuan Wang, The Affiliated Hospital of Qingdao University, China Updates Copyright 2026 Pang, Zou, Lu, Li, Chen, Zhu, Wang, Shi and Kang

Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress