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Additionally, butyrate activates GPR109a signaling, which confers anti-inflammatory properties to macrophages and DCs, thereby promoting the accumulation of Tregs and IL-10-producing CD4 + T cells in the colon ( Table 2 )

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While astrocytes primarily synthesize Gln, neurons uptake Gln, which is then reconverted into Glu by glutaminase [4]

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