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While the spheroids treated with Ru(II)-OH or NP2 in a 1% O 2 atmosphere majorly consisted of living cells, the spheroids treated with NP4 in a 1% O 2 atmosphere consisted of dead cells (Fig

Gamma-glutamyl transpeptidase in nucleated cells can be determined using the method described by Wright et al

This strategy suits users who achieved satisfactory improvements wanting to preserve results without full continuous intensity, willing to accept moderate benefit levels (70-85% of peak) rather than maximum continuous optimization, seeking to minimize costs while maintaining most improvements, and wanting simpler approach than complex cycling schedules

Each subject received their assigned capsules in identical packages at weeks 0, 4, and 8, with 30 capsules per visit (two extra capsules per package)