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Tirzepatide from a 503B facility generally benefits from more rigorous quality assurance, which can translate to more reliable shelf life through the stated BUD

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10.1126/science.276.5309.60 Science 63 MirandaO.FarooquiM.SiegfriedJ

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It implies controlled studies in human beings, with defined endpoints, that tell us whether a compound does what it is claimed to do

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Bottom line: even if the FDA eventually recommends that certain peptides can be compounded under Section 503A, many stakeholders could still be blocked by the requirement to source pharmaceutical-grade API from an FDA-registered establishment with a Certificate of Analysis and by FDAs demonstrated willingness to police marketing claims around compounded drugs

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