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doi:10.1177/2309499020905993

& Eishi, Y

Localized (Intra-Articular Injection): For joint-specific injuries like a meniscus tear, some research protocols involve injecting the compound directly into the joint capsule

Furthermore, IL-1, TNF-, and complement component subunit 1q (C1q) encourage the transformation of astrocytes into reactive astrocytes (A1), subsequently impairing the astrocytic capacity to regulate microglial activity [132]