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The only form of cortisol that is physiologically active is in its unbound form, which is detected in plasma and is removed either by tissue absorption or by molecular breakdown that releases cortisone 84
Available online: [DOI] [PMC free article] [PubMed] [Google Scholar] 117.Bellin M.D., Abu-El-Haija M., Morgan K., Adams D., Beilman G.J., Chinnakotla S., Conwell D.L., Dunn T.B., Freeman M.L., Gardner T., et al
Hypertension 71 , 10561063 (2018)