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Journal of Clinical Biochemistry and Nutrition, 61 (1), 3339

In terms of targeting cancers ability for extracellular cholesterol uptake, inhibiting cholesterol receptors LDLR and SR-B1 may not be enough, since cholesterol can also be taken up by cancer cells via macropinocytosis [7]

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It downregulates NLRP3 inflammasome activity, suppresses the TLR4/NF-B axis, and activates the Nrf2/HO-1 signaling cascade, offering neuroprotection and reducing inflammation in various animal models (Althagafy et al