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Concretely, lactylation of PDHA1 at K336 and CPT2 at K457/8 results in the inactivation of both enzymes and the inhibition of OXPHOS by restricting acetyl-CoA influx from pyruvate and fatty acid oxidation, respectively

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Additionally, the lower concentration of benzyl alcohol found in bacteriostatic water for peptide reconstitution prevents it from affecting the stability or integrity of the peptide being dissolved in it