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Captopril has been revealed to facilitate the GSH system in several rodent models of myocardial injuries, such as clozapine and DOX-induced damage models, thereby protecting cardiomyocytes from oxidative stress [239, 240]

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Their ability to target multiple pathwaysfrom initiating apoptosis and detoxifying carcinogens to reprogramming epigenetics and the tumor microenvironmentpositions ITCs as attractive candidates for integrative oncology approaches (113)