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The long-term effects on growth hormone secretion are of specific interest, as sustained rise of IGF-1 levels (whether from endogenous or exogenous sources) can suppress growth hormone release through negative feedback at the hypothalamic and pituitary levels

Without adequate NAD levels, cells cannot efficiently generate ATP, the primary energy currency of the body

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Li J, Li Y, Wang Z et al (2025a) Oxytocin intervention mitigates pathological and behavioral impairments in APP/PS1 mice subjected to early social isolation