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Between the esophagus and the stomach is a critically important valve, the lower esophageal sphincter (LES)

These research methods can deeply enhance the level of human physiological and pathological cognition, explain the scientific connotation of Chinese medicine syndromes, and reveal the effective material basis and functional mechanisms of herbal medicines, thereby promoting its clinical translation (Zhang et al., 2024)

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In a clinical trial, voxelotor was well-tolerated up to 2800 mg, but 1500 mg once daily was recommended for SCD patients without comorbidities