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For this FY 2024 IPPS/LTCH PPS proposed rule, we received a similar request to reassign cases describing the insertion of a neurostimulator generator into the skull in combination with the insertion of a neurostimulator lead into the brain from MS-DRG 023 to MS-DRG 021 or reassign all cases currently assigned to MS-DRG 023 that involve a craniectomy or a craniotomy with the insertion of device implant and create a new MS-DRG for these cases

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BDNF and GABAergic systems that are involved in critical CNS functions, ranging from neuronal development and neuronal survival to learning and memory [47, 48]

Additionally, it plays a role in enzymatic functions essential for growth, development and overall cellular repair