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The results indicated that pretreatment with 10 M ERK1/2 inhibitor obviously antagonized, while pretreatment with 10 M JNK inhibitor and 10 M p38 inhibitor had no effect on, BPC-157-induced proliferation, migration, and tube formation

Not one of these drugs are curative, and their long-term use often causes severe side effects including cancer

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While agonist peptides based on either scaffold are potent in rat obesity models 2,10,11,12,13 , only a transient weight loss effect is observed with sCT in mouse diet-induced obesity (DIO) models 14 , indicating that there may be distinctions in the mode of action of individual dual agonists