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[42] [43] El glutatin es un componente intracelular fuertemente regulado y limitado en su produccin debido a la inhibicin de retroalimentacin negativa de su propia sntesis a travs de la enzima gamma-sintetasa glutamilcistena

Commonly reported triggers include spicy foods, citrus fruits, tomatoes, chocolate, caffeinated drinks, alcohol, artificial sweeteners, overexertion, prolonged sitting, exercises that work the abdominal muscles (eg, sit-ups and crunches), riding a bicycle or horse, sexual activity, and wearing tight clothing