Figure 3 Despite the clinical evidence for microbial infection in AD, other neurodegenerative diseases such as Parkinsons disease and ALS also are influenced by microbial infections and induction of inflammatory processes with microglial and astrocytic activation (Lotz et al., 2021), which would question the primacy of microbes in AD
Despite these limitations, uricases have the potential to become a primary therapeutic option for severe and challenging cases of hyperuricemia
They act as signals telling specific tissues to repair, telling the immune system to calm down, telling the body to rebuild whats been broken
Mack CM, Soares CJ, Wilson JK, Athanacio JR, Turek VF, Trevaskis JL, et al