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Key challenges for clinical translation include the lack of consistent benefit, as large RCTs and systematic meta-analyses have failed to demonstrate efficacy of prebiotics/probiotics in ICU patients despite encouraging signals in individual studies ( 6 Limitations and future perspectives Despite growing recognition of ferroptosis in vascular injury, several fundamental limitations hinder its clinical translation

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2006, 7: 8-doi:10.1186/1471-2156-7-8 Serajee FJ, Nabi R, Zhong H, Huq AHMM: Polymorphisms in xenobiotic metabolism genes and autism