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Recordings were made using an Axopatch 200B amplifier (Molecular Devices), filtered at 10 kHz, digitized at 20 kHz using pClamp 9.2 (Digidata Interface, Molecular Devices), and analyzed off-line using Clampfit 9.2

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Thus there is a large body of evidence that the increased dopamine release in the nucleus accumbens and forebrain structures is the major factor producing the rewarding, conditional reinforcement and reinforcement enhancing effects of nicotine

Measurements: 105 mm by 94 mm by 146 mm (4.15 x 3.68 x 5.75 Inches)