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CSF-cNs are highly likely to take a large amount of iron from CSF to generate ROS

The platelet intracellular calcium response to serotonin is augmented in bipolar manic and depressed patients

It will then systematically discuss the upstream regulatory mechanisms of GPX4 in the context of OA, including the System Xc and nuclear factor erythroid 2-related factor 2(Nrf2) signaling pathways, as well as its downstream biological effects, such as impacts on chondrocyte survival, inflammatory responses, and ECM metabolism