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That literature is useful for topical context

In addition, stroke, epilepsy, brain trauma and spinal cord injury cause secondary fatigue (15,18,19)

Hydration, smaller meals, and avoiding fatty or spicy foods are commonly reported supportive measures

Its concentration in human plasma is reported to decline substantially from young adulthood into later middle age, a decline that Pickarts later reviews use as the conceptual rationale for reintroducing the peptide