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The IGF-1/IGF-1R axis can also induce phosphorylation of ER through ribosomal S6 kinase 1 (S6K1), downstream of the PI3K/AKT/mTOR pathway which results in the upregulation of IGF-1, IGF-1R and other ER target genes (Kim et al., 2007)

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Gastroenterology 158 (2), 322340

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The primary cilia of nerve cells can sense and respond to the changes of the local extracellular environment

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[DOI] [PubMed] [Google Scholar] 259.Luis R, Brito C, Pojo M

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