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Yaffe, K

As horses age or endure repetitive high-impact activities, the cartilage and connective tissues in their joints can begin to deteriorate

What to avoid when taking glutathione To get the most from glutathione, it helps to reduce the things that deplete it: Alcohol heavily depletes glutathione and burdens the liver Smoking a major source of oxidative stress Excess processed and fried food increases free-radical load Poor sleep and chronic stress both lower natural production There aren't many strict "don't combine with X" rules for healthy adults, but if you take regular medication, have a medical condition, or are pregnant or breastfeeding, talk to your doctor first (see disclaimer below)

Any reduction in cysteine availability directly translates to reduced glutathione synthesis