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The trend-level negative association between urinary cotinine and WB SUV is consistent with much prior research demonstrating that cotinine reduces neuroinflammation [75, 76]

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adults have high blood pressure, which is when the systolic pressure (the top number in a blood pressure reading) is at least 130 millimeters Hg (mercury) or the diastolic pressure (bottom number) is 80 mm Hg or more

Cotinine is the ideal biomarker for tobacco exposure because its only present after the body has processed nicotine and boasts a significantly longer half-life of 15 to 20 hours