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Due to the complex pathogenesis of the disease, which involves autoimmunity, genetics, inflammation and oxidative stress in the bodys tissues, the current drug therapy generally targets a single molecule, and effective and efficient drugs involving multiple levels and targets are lacking

doi: 10.3322/caac.21834 3

Each peptide has its own job, but they work in concert to rebuild and repair tissue far more effectively than any single one could alone

The use of Drosophila bring to the study of oxidative liver injury many advantages, including ease of genetic manipulation, availability of genetic mutants and constructs, ease of germ-free generation, relatively short lifespan, amenability to high-throughput screening, and overall cost relative to murine models 40