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doi: 10.1016/j.celrep.2015.09.036 122 StoneTWWilliamsRO

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Pyruvate kinase (PK) is the most common enzymopathic cause of chronic hemolysis, followed by glucose phosphate isomerase deficiency (GPI), and pyrimidine 5 nucleotidase-1 (P5N1), which is essential for removal of toxic nucleotide precursors

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