The introduction of the discreet and sleek appearing pod-based systems in 2015 led to a rapid rise in use of e-cigarettes by adolescents
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These cases are now known collectively as e-cigarette, or vaping, product useassociated lung injury (EVALI).[4,5] As of November 2019, there have been more than 2800 cases of EVALI in North America, which have displayed a heterogeneous pattern of lung pathology that includes organizing pneumonia, acute respiratory distress syndrome, acute eosinophilic pneumonia, lipoid pneumonia, diffuse alveolar damage, diffuse alveolar hemorrhage, and hypersensitivity pneumonitis.[6] Given the increased incidence and potential severity of EVALI, renewed focus has been placed on the pathophysiology and corresponding health effects of vaping, and on the need for product regulation
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