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If pregnant, breast-feeding or planning to become pregnant, consult your physician before use

However, as with other lipid-based nanosystems, key challenges remain, including ensuring long-term formulation stability, evaluating safety with repeated topical application, and scaling up production for clinical-grade batches [123, 124, 134]

Regular moderate exercise can boost glutathione production and enzyme activity, though overtraining may deplete it

Therefore, they speculated that caffeic acid probably acts as a major player in the preventive effect of chlorogenic acid against oxidative damage in ischemiareperfusion intestinal tissue [170]