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2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS ) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe2+), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation

Like any supplement, berberine comes with potential side effects: Because of this, anyone taking prescription medications should consult an endocrinologist before starting berberine

A total of 44 men participated, randomly divided into three groups: one received tomato juice, one received antioxidant capsules, and one was a control group with no supplements

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