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Key Takeaways If youre short on time, heres a quick summary to understand the key differences between 503As and 503Bs right away: 503A compounding pharmacies compound medications according to individual patient prescriptions, which may be intended for either at-home use or administration in a healthcare setting, while 503B outsourcing facilities compound drugs in larger batch sizes under cGMP with or without patient-specific prescriptions to be distributed (generally) to healthcare facilities for office use