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Unlike humans, dogs have a much lower threshold for nicotine toxicity, which means that even small doses can be fatal, especially for puppies or small breeds

Journal of Consulting and Clinical Psychology, 64 (6), 1152

After 15 years: The risk of heart disease is equal to that of a person who has never smoked

In a large randomized trial conducted in Kenya, he and his colleagues found that combining medication with a specialized counseling program dramatically increased long-term quit rates among people with HIV who smoked an outcome that could significantly reduce tobacco-related deaths in this vulnerable population