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The number of gestational weeks in the PE group was lower than that in the CTL group ( P = 0.001 ), and age ( P = 0.029 ), prenatal BMI ( P 0.05 )

This prevents over-saturating the nasal membrane

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Factors conferring relative protection to children from the toxic effect of paracetamol overdose include increases in paracetamol sulphation capacity [44,45,46,47,48], relative immaturity of the CYP450 oxidation system [15, 46, 49, 51] and the larger relative liver volume found in children [59] but these theoretical mechanisms have not been confirmed