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Multisystemic manifestations include hearing loss, musculoskeletal problems (contractures, joint stiffness, hip dysplasia and scoliosis), respiratory tract infections, and valvular cardiac disease ( Neuronal Ceroid Lipofuscinoses Neuronal ceroid lipofuscinoses (NCL) are a group of autosomal recessive, progressive lysosomal storage disorders with dominantly neurological symptomatology

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