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At 48 weeks, a large majority of participants on the higher doses achieved reductions of 10% or more

After this time, depending on the cause of your vitamin B12 deficiency, you may need to take it continuously for life (if you have pernicious anaemia or are on a vegan diet), or just for a few months until your vitamin B12 levels return to normal

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doi:10.1542/peds.2008-1173