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In women, up to 12 months of use showed no evidence of tissue changes or serious issues emerging.There was no accumulation of effects on blood pressure or heart rate with ongoing use the cardiovascular effects remained transient

[DOI] [PMC free article] [PubMed] [Google Scholar] 278.Udovicic M., Sever M., Kavur L., Loncaric K., Barisic I., Balenovic D., Zivanovic Posilovic G., Strinic D., Uzun S., Batelja Vuletic L., et al

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