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These injections, usually containing hydroxocobalamin or cyanocobalamin, are administered intramuscularly, thus bypassing the digestive system where the absorption problem occurs

Whelton PK (2018): 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines

Accordingly, sex-dependent differences in xenobiotic metabolism are well documented in rats, with greater responses generally seen in males (Mugford and Kedderis, 1998) and with responses influenced by circulating levels of growth hormone (Ahluwalia et al