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A randomised placebo-controlled trial (RCT) including 42 participants with schizophrenia, who were experiencing an acute phase of symptomatology, were randomly assigned to receive up to 2 g/d of NAC plus up to 6 mg/d of risperidone for 8 weeks as an adjunct intervention

On the basis of a data-driven identification of optimal neural biomarkers of symptoms, cortical electrodes were used to extract real-time neural signals in three participants and four independently controlled hemispheres, serving as control signals in the aDBS control system