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Pharmacokinetics of nanoparticles: current knowledge, future directions and its implications in drug delivery

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Studies on the use of non-denaturing agents such as N -lauryl sarcosine, dimethyl sulfoxide (DMSO), 5% n -propanol, mild non-ionic detergents, high pH buffers, and low denaturant concentration that preserve the native-like state of the fusion proteins have been reported [52,53,54,55,56,57]