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10.1016/s8756-3282(98)00180-x 99 SeiwerthS.BrcicL.VuleticL

During ethanol oxidation ROS production increases dramatically due to induction of CYP2E1 and by activation of Kupffer cells in the liver

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The specific regulation of inflammatory cytokine balance in the reproductive organs by kaempferol indicates a tissue-specific immune-modulatory effect, which is particularly important for late laying hens because it alleviates local inflammation in the ovary and uterus without altering systemic immune parametersthus avoiding potential immunosuppression or immune hyperactivation