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Contraindications to Liver Transplant Absolute contraindications Extrahepatic malignancy unless tumor-free for 2 y and low probability of recurrence Untreated alcoholism Uncontrolled sepsis Severe multiorgan failure Severe psychologic disease likely to affect adherence to therapy Severe pulmonary hypertension Advanced cardiopulmonary disease AIDS Hepatocellular carcinoma or perihilar cholangiocarcinoma with metastasis In addition, adult patients with any of the following diagnoses are eligible for the standardized MELD score exception based on the median MELD at transplant policy: hepatopulmonary syndrome, primary hyperoxaluria, familial amyloidosis, perihilar cholangiocarcinoma, cystic fibrosis, and portopulmonary hypertension

It plays a critical role in extracellular matrix remodeling, telling your cells to produce more collagen, elastin, and proteoglycans

They are among the most clinically studied peptides in modern medicine

Medically reviewed by Rhonda Collins, FNP-C | Mito Health on April 30, 2026