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on euthyroid patients with Hashimotos disease showed that markers of oxidative stress (evaluated through advanced glycation end-products - AGEs) were significantly higher in patients compared to controls, and the activity of the enzymes glutathione peroxidase and thioredoxin reductase, as well as plasma antioxidant activity, was reduced in the patients compared to controls

It has demonstrated a strong safety profile and is currently used for non-therapeutic experimental applications only

This short term program duration can be between 30 days 6 months, depending on patients plan of care

The phosphorylation status of P53 was also assessed in whole-cell lysates