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Delivery of circ-Snhg11 from hypoxia-pretreated adipose-derived stem cell-originating exosomes (ADSC-HExo)-embedded GelMA hydrogels (GelMA-HExo) can improve EC survival and function by activating miR-144-3p/NFE2L2/HIF1 signaling, implicating the role of ADSC-Exos in diabetic wound healing (231)

10.1016/j.phymed.2024.155554 Summary Keywords Chinese medicine, natural metabolites, CVDs, flavonoids, alkaloids, saponins Citation Liu X, Zhang W, Miao X and Hu Y (2025) Natural metabolites used in traditional Chinese medicine for cardiovascular diseases: pharmacological mechanisms, evidence, and future directions

When the brain perceives stress, it signals the adrenal glands to release cortisol, the body's primary stress hormone

For example, Trichophyton verrucosum secreted keratinases that degraded hair and keratin, causing focal alopecia and crusted dermatitis