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Dimensions: 2439 x 3658 px | 20.7 x 31 cm | 8.1 x 12.2 inches | 300dpi Date taken: 9 February 2020 Location: Chinatown, New York, USA

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Furthermore, clinical trials have shown that standard NRT doses are inadequate for rapid metabolizers of nicotine (i.e., those who inactivate nicotine to cotinine and then to 3-hydroxycotinine [3-HC] more quickly than others due to genetic variation affecting the activity of the hepatic enzyme CYP2A6) [20, 25]