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Moreover, enhanced expression of drug resistance markers [P-gp, BCL2-related protein A1 (BCL2A1), Excision Repair Cross-Complementation Group 1 (ERCC1), Glutathione S-transferase pi 1 (GSTP1)] was noted in AGSR and HGC-27R cells ( Figures 1B and S1B ), indicating successful construction of PTX-resistant GC cell models

Authoritative Sources PubMed abstract for the phase 2 cagrilintide trial summarizes studied dose groups and research outcomes