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Derivatives of the anticoagulant heparin have also been investigated in the context of sickle cell pain crisis and have met with some success and may help prevent crises, though more studies are needed to confirm these findings (Qari 2007

Another possible strategy to delay aging is to express a lysosome-targeted transmembrane proton-motive force-driven transhydrogenase, such as a mammalian NNT homolog, with the nucleotide binding domain facing the cytoplasm (Figure 3B)