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doi: 10.2174/138955711795305335 152
Studies examining ovariectomized, hormone-primed female rats showed: Dramatic increases in solicitation behaviors (hopping, darting, ear-wiggling) at doses of 100-200 mcg/kg No effects on consummatory behaviors such as lordosis Selective enhancement of proceptive (desire-related) behaviors without affecting receptivity Effects mediated through the medial preoptic area, as direct mPOA injections replicated systemic effects These findings established PT-141 as the first pharmacological agent demonstrating selective appetitive sexual behavior enhancement in preclinical models
To provide more treatment options, new medicines have been studied that impact a different neurotransmitter in the brain, that is, glutamate
Fleas reproduce quickly and have a complex life cycle, so they can be problematic to eliminate
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