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developed a recombinant VNP20009 strain that, under near-infrared (NIR) light stimulation, activates the production and release of interferon INF-, which, when combined with photodynamic therapy (PDT), achieves a synergistic immune therapy effect and suppresses distant tumor growth [322]

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By clearing out senescent cells, FOXO4-DRI decreases the production of inflammatory signals, promotes tissue repair, and restores a healthier cellular environment, effectively reducing chronic inflammation and its negative effects on the body (7)

Toxicity outcomes vary based on particle characteristics (type, size, and surface chemistry), exposure dose and duration, organismal factors (age, sex, species), and co-exposure to other pollutants