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As such GGT plays an integral role in GSH homeostasis and has been traditionally regarded as a component of the cellular defense system against oxidative stress (Pompella et al., 2007)

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Molecular mechanisms of metastasis The genes, which allow transformed cells to invade the surrounding tissue and attract a supportive stroma, can be defined as metastasis initiation genes and could promote cell motility, EMT, extracellular matrix degradation, bone marrow progenitor mobilization, angiogenesis or evasion of the immune system

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