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Likewise, also important for multiple sclerosis therapy, natalizumab also carries a specific risk of progressive multifocal leucoencephalopathy and reactivation of JC virus infection (24)

Higher-Caution Situations Extra medical supervision is important if you: have a history of reactions to injectable vitamins/cobalamins have significant kidney or liver disease are pregnant or breastfeeding are offered a compounded MIC B12 product without clear labeling of ingredients, concentrations, and compounding source The FDAs overview of compounding helps explain why quality can vary (see Compounding and the FDA: Questions and Answers )